Molecular Genetics Research Associate/Instructor Position in Functional Genetics at Brigham and Women’s Hospital
A Research Associate or Instructor position in functional genetics is available beginning March 1, 2009 at the Channing Laboratory and the Pulmonary Division and the Respiratory Genetics Research Center of the Brigham and Women’s Hospital. The Research Associate/Instructor with will be responsible for functional evaluation of disease-associated sequence variants identified from integrative genomic and genome-wide association studies in asthma, chronic obstructive pulmonary disease (COPD), and other disorders of the respiratory system. Specific responsibilities will include design and execution of studies to characterize the functional properties of disease-related variants, to supervise laboratory technicians assisting with these studies, and to assist faculty in the training of doctoral and postdoctoral researchers in these methods.
Requirements: Applicants must have a Ph.D. degree or the equivalent in hand and be eligible for employment in the United States (citizenship, residency, or work visa). At least two years of full-time post-doctoral training. Laboratory skills and prior work experience must include proficiency with molecular and cellular biology techniques, including cell culture, overexpression studies (including reporter assay construction and viral transfection and transduction studies), nuclear protein extraction and gel retardation assays, gene cloning, siRNA gene silencing, and characterization of differential splicing patterns.
Preference will be given to candidates with additional experience with allelic imbalance assays.
Interested applicants are instructed to provide a curriculum vitae via email, and arrange two letters of reference, which should be addressed to the following:
Scott T. Weiss, MD, MS Professor of Medicine Channing Laboratory Brigham & Women’s Hospital 181 Longwood Ave Boston, MA 02115 Tel: 617-525-2278 Fax: 617-525-0958 Email: scott.weiss@channing.harvard.edu
Augustine M. Choi, MD Parker Francis Professor Chief, Pulmonary& Critical Care Med Brigham & Women’s Hospital 75 Francis Street Boston, MA 02115
Edwin K. Silverman, MD, PhD Associate Prof of Medicine Channing Laboratory Brigham & Women’s Hospital 181 Longwood Avenue Boston, MA 02115
Brigham and Women’s Hospital and Harvard Medical School are equal opportunity employers and strongly encourage application from women and minority candidates.