The access to the city center (Sannomiya) is easy. It takes only 20 minutes by train. Even by driving a car, 30 minutes is enough to get the center of Kobe. Access to Osaka, it takes 45 minutes by train and 60 minutes by car.
To the Kansai International Airport, a limousine bus leaves at Sannomiya and takes 65 minutes to the airport.