Katakana = Angel Street (enjeru sutori-to)
Line 2 = Be mindful of pedestrians (kind of a loose translation, because the literal translation of "go easy on pedestrians" just sounds strange)
Line 3 = Please proceed while pushing your bicycle (although in English you'd probably see more signs stating "Please don't ride your bike down this street" or something similar)
Is this cartoon illustration display unique to Kyoto, Japan in a community that is popular (or often crowded) with elderly who are 90-100 years young?
Or is the sign intended for many young people (younger people prefer to move more quickly and are mostly couples) who are inadvertently annoying the older people in this pedestrian only community?
There's nothing on that sign to indicate it's exclusive to Kyoto. But, if you look at the far right side of the picture, to the right of the sign, there's a sign that says 「新京極」 → Shinkyogoku, which is a shopping district in Kyoto.
In my experience I wouldn't say the sign is strictly aimed at younger people flying down the streets on their bicycles. I've seen plenty of old men and women flying through crowded places on their bicycles, loudly ringing the bells in hopes that the pedestrians will dive out of their way