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ぴかぴか(新しい)信頼のおけるダイエット情報?ぴかぴか(新しい)

管理人のプリンは、大学生ですペンギン

心理学を専攻していて、今日心理学の授業を受けていたら、健康心理学?(痩せる意味でのダイエットを研究しているらしい)の先生が、

「飲むだけで体重が減る薬は、論理学上出来るはずが無い、」と言っていました。

この先生がいう限り、ダイエット薬を買うのは止めた方がいいと思いますウインク


ぴかぴか(新しい)信頼のおけるダイエット情報?ぴかぴか(新しい)

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Boschmann M. Thielecke F. The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study. [Journal Article. Randomized Controlled Trial] Journal of the American College of Nutrition. 26(4):389S-395S, 2007 Aug.
SLU-MCL has current print and/or online access; check Library Holdings
UI: 17906192
Authors Full Name
Boschmann, Michael. Thielecke, Frank.

OBJECTIVES: The development of obesity is characterized by an increase in adipose tissue mass and by concomitant and profound changes in almost all organ functions leading to diseases such as hypertension, diabetes mellitus and coronary heart disease. Recent data from human studies indicate that the consumption of green tea and green tea extracts may help reduce body weight, mainly body fat, by increasing postprandial thermogenesis and fat oxidation. However, human studies investigating the metabolic effects of the most predominant tea catechin, EGCG, alone are absent. METHODS: In a randomized double blind, placebo-controlled, cross-over pilot study, six overweight men were given 300 mg EGCG/d for 2d. Fasting and postprandial changes in energy expenditure (EE) and substrate oxidation were assessed. RESULTS: Resting EE did not differ significantly between EGCG and placebo treatments, although during the first postprandial monitoring phase, respiratory quotient (RQ) values were significantly lower with EGCG compared to the placebo. CONCLUSIONS: These findings suggest that EGCG alone has the potential to increase fat oxidation in men and may thereby contribute to the anti-obesity effects of green tea. However, more studies with a greater sample size and a broader range of age and BMI are needed to define the optimum dose.



Diepvens K. Kovacs EM. Nijs IM. Vogels N. Westerterp-Plantenga MS. Effect of green tea on resting energy expenditure and substrate oxidation during weight loss in overweight females. [Journal Article. Research Support, Non-U.S. Gov't] British Journal of Nutrition. 94(6):1026-34, 2005 Dec.
SLU-MCL has current print and/or online access; check Library Holdings
UI: 16351782
Authors Full Name
Diepvens, Kristel. Kovacs, Eva M R. Nijs, Ilse M T. Vogels, Neeltje. Westerterp-Plantenga, Margriet S.

We assessed the effect of ingestion of green tea (GT) extract along with a low-energy diet (LED) on resting energy expenditure (REE), substrate oxidation and body weight as GT has been shown to increase energy expenditure and fat oxidation in the short term in both animals and people. Forty-six overweight women (BMI 27.6 (sd 1.8) kg/m2) were fed in energy balance from day 1 to day 3, followed by a LED with GT (1125 mg tea catechins +225 mg caffeine/d) or placebo (PLAC) from day 4 to day 87. Caffeine intake was standardised to 300 mg/d. Energy expenditure was measured on days 4 and 32. Reductions in weight (4.19 (sd 2.0) kg PLAC, 4.21 (sd 2.7) kg GT), BMI, waist:hip ratio, fat mass and fat-free mass were not statistically different between treatments. REE as a function of fat-free mass and fat mass was significantly reduced over 32 d in the PLAC group (P<0.05) but not in the GT group. Dietary restraint increased over time (P<0.001) in both groups, whereas disinhibition and general hunger decreased (P<0.05). The GT group became more hungry over time and less thirsty, and showed increased prospective food consumption compared with PLAC (P<0.05). Taken together, the ingestion of GT along with a LED had no additional benefit for any measures of body weight or body composition. Although the decrease in REE as a function of fat-free mass and fat mass was not significant with GT treatment, whereas it was with PLAC treatment, no significant effect of treatment over time was seen, suggesting that a robust limitation of REE reduction during a LED was not achieved by GT.



Diepvens K. Kovacs EM. Vogels N. Westerterp-Plantenga MS. Metabolic effects of green tea and of phases of weight loss. [Journal Article. Randomized Controlled Trial. Research Support, Non-U.S. Gov't] Physiology & Behavior. 87(1):185-91, 2006 Jan 30.
UI: 16277999
Authors Full Name
Diepvens, K. Kovacs, E M R. Vogels, N. Westerterp-Plantenga, M S.

The effect of ingestion of green tea (GT) extract along with a low-energy diet (LED) on health-related blood parameters, and the relationships among changes in metabolic parameters and phases of weight loss were assessed. A double-blind, placebo-controlled, parallel design was used. 46 female subjects (BMI 27.7+/-1.8 kg/m(2)) were fed in energy balance from days 1 to 3, followed by a LED with GT (n=23) or placebo (PLAC, n=23) from days 4 to 87. The LED-period consisted of a phase 1 of 4 weeks (days 4-32) followed by a phase 2 of 8 weeks (days 32-87). Body composition and fasting blood samples were determined on days 4, 32 and 87. No significant differences were observed between the blood parameters of the PLAC and GT group. In phase 1 compared to phase 2 the rate of weight loss was 0.09+/-0.05 kg/day vs. 0.03+/-0.03 kg/day (p<0.001); Fat free mass (FFM) was 21% of weight loss in phase 1 vs. 7% in phase 2 (ns). Surprisingly, favourable changes in free fatty acids, triacylglycerol, beta-hydroxybutyrate, glucose and total cholesterol in phase 1 were reversed in phase 2 (p<0.01). Taken together, GT supplementation during a LED had no effect on health-related blood parameters. Initial improvements in several blood measures at day 32 were reversed by day 87, despite continued weight loss. Modest weight loss improved HDL cholesterol and blood pressure.



Greenberg JA. Boozer CN. Geliebter A. Coffee, diabetes, and weight control. [Review] [134 refs] [Journal Article. Review] American Journal of Clinical Nutrition. 84(4):682-93, 2006 Oct.
SLU-MCL has current print and/or online access; check Library Holdings
UI: 17023692
Authors Full Name
Greenberg, James A. Boozer, Carol N. Geliebter, Allan.

Several prospective epidemiologic studies over the past 4 y concluded that ingestion of caffeinated and decaffeinated coffee can reduce the risk of diabetes. This finding is at odds with the results of trials in humans showing that glucose tolerance is reduced shortly after ingestion of caffeine or caffeinated coffee and suggesting that coffee consumption could increase the risk of diabetes. This review discusses epidemiologic and laboratory studies of the effects of coffee and its constituents, with a focus on diabetes risk. Weight loss may be an explanatory factor, because one prospective epidemiologic study found that consumption of coffee was followed by lower diabetes risk but only in participants who had lost weight. A second such study found that both caffeine and coffee intakes were modestly and inversely associated with weight gain. It is possible that caffeine and other constituents of coffee, such as chlorogenic acid and quinides, are involved in causing weight loss. Caffeine and caffeinated coffee have been shown to acutely increase blood pressure and thereby to pose a health threat to persons with cardiovascular disease risk. One short-term study found that ground decaffeinated coffee did not increase blood pressure. Decaffeinated coffee, therefore, may be the type of coffee that can safely help persons decrease diabetes risk. However, the ability of decaffeinated coffee to achieve these effects is based on a limited number of studies, and the underlying biological mechanisms have yet to be elucidated.


Seeram NP. Henning SM. Niu Y. Lee R. Scheuller HS. Heber D. Catechin and caffeine content of green tea dietary supplements and correlation with antioxidant capacity. [Journal Article] Journal of Agricultural & Food Chemistry. 54(5):1599-603, 2006 Mar 8.
UI: 16506807
Authors Full Name
Seeram, Navindra P. Henning, Susanne M. Niu, Yantao. Lee, Rupo. Scheuller, H Samuel. Heber, David.

The health benefits associated with tea consumption have resulted in the wide inclusion of green tea extracts in botanical dietary supplements, which are widely consumed as adjuvants for complementary and alternative medicines. Tea contains polyphenols such as catechins or flavan-3-ols including epicatechin, epigallocatechin, epicatechin gallate, and epigallocatechin gallate (EGCG), as well as the alkaloid, caffeine. Polyphenols are antioxidants, and EGCG, due to its high levels, is widely accepted as the major antioxidant in green tea. Therefore, commercial green tea dietary supplements (GTDS) may be chemically standardized to EGCG levels and/or biologically standardized to antioxidant capacity. However, label claims on GTDS may not correlate with actual phytochemical content or antioxidant capacity nor provide information about the presence and levels of caffeine. In the current study, 19 commonly available GTDS were evaluated for catechin and caffeine content (using high-performance liquid chromatography) and for antioxidative activity [using trolox equivalent antioxidant capacity (TEAC) and oxygen radical antioxidant capacity (ORAC) assays]. Product labels varied in the information provided and were inconsistent with actual phytochemical contents. Only seven of the GTDS studied made label claims of caffeine content, 11 made claims of EGCG content, and five specified total polyphenol content. Caffeine, EGCG, and total polyphenol contents in the GTDS varied from 28 to 183, 12-143, and 14-36% tablet or capsule weight, respectively. TEAC and ORAC values for GTDS ranged from 187 to 15340 and from 166 to 13690 mumol Trolox/g for tablet or capsule, respectively. The antioxidant activities for GTDS determined by TEAC and ORAC were well-correlated with each other and with the total polyphenol content. Reliable labeling information and standardized manufacturing practices, based on both chemical standardization and biological assays, are recommended for the quality control of botanical dietary supplements.


Accession Number Peer Reviewed Journal: 2005-09681-011.

Title Body Weight Loss and Weight Maintenance in Relation to Habitual Caffeine Intake and Green Tea Supplementation. [References].

Year of Publication 2005

Author Westerterp-Plantenga, Margriet S; Lejeune, Manuela P. G. M; Kovacs, Eva M. R.

E-Mail Address Westerterp-Plantenga, Margriet S.: m.westerterp@hb.unimaas.nl

Source Obesity Research. Vol 13(7) Jul 2005, 1195-1204.

Other Serial Titles Obesity

Abstract Objective: Investigation of the effect of a green tea-caffeine mixture on weight maintenance after body weight loss in moderately obese subjects in relation to habitual caffeine intake. Research Methods and Procedures: A randomized placebo-controlled double blind parallel trial in 76 overweight and moderately obese subjects, (BMI, 27.5 2.7 kg/msuperscript 2) matched for sex, age, BMI, height, body mass, and habitual caffeine intake was conducted. A very low energy diet intervention during 4 weeks was followed by 3 months of weight maintenance (WM); during the WM period, the subjects received a green tea-caffeine mixture (270 mg epigallocatechin gallate + 150 mg caffeine per day) or placebo. RESULTS: Subjects lost 5.9 1.8 (SD) kg (7.0 2.1%) of body weight (p < 0.001). At baseline, satiety was positively, and in women, leptin was inversely, related to subjects' habitual caffeine consumption (p < 0.01). High caffeine consumers reduced weight, fat mass, and waist circumference more than low caffeine consumers; resting energy expenditure was reduced less and respiratory quotient was reduced more during weight loss (p < 0.01). In the low caffeine consumers, during WM, green tea still reduced body weight, waist, respiratory quotient and body fat, whereas resting energy expenditure was increased compared with a restoration of these variables with placebo (p < 0.01). In the high caffeine consumers, no effects of the green tea-caffeine mixture were observed during WM. Discussion: High caffeine intake was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in women. In habitual low caffeine consumers, the green tea-caffeine mixture improved WM, partly through thermogenesis and fat oxidation. (PsycINFO Database Record (c) 2007 APA, all rights reserved) (journal abstract)

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