>But first of all, you need to understand that their current methods don’t involve simply freezing brains. They are freezing brains and perfusing them with glutaraldehyde to fix them, better preserving the ultrastructure of the tissue. Every microscopists does this; I was fixing zebrafish brains with a cocktail of acrolein, glutaraldehyde, and paraformaldehyde in the 1980s, trying to capture detailed images of synapses in the spinal cord. It worked pretty well, too. They know what they are getting out of this: an aldehyde-preserved brain.
What I didn’t do with my experiments in aldehyde-preserved brains was claim that I was preserving all the information necessary for nervous system function. I was quite aware that I was chemically nuking all the proteins in the tissue; I was washing out most of the chemistry; I was destroying most of the physiological information to preserve a structural skeleton of what was there, so I could see the physical arrangement of the pieces. Nothing more.
Neuroscience does not suggest that fixing a brain in aldehydes will preserve “memories, identity, and a substrate for future consciousness”. There’s no reason to think their methods create “appropriately preserved brains”.
Ken Hayworth氏の主張している内容の生データが公開されていないところに僅かな可能性があるように思えますけど、実はこの結果は調査するまでもないぐらいに、当たり前の結果なのです。今さら指摘すること自体、遅すぎて意味のないことだと思います(それでも、Ken Hayworth氏が指摘するのは、疑似科学に騙されている人々が、まだ少人数とはいえいるからでしょう)。M22では脳神経系を保存できないことは、最初から分かりきっていた結果なのですよ。M22よりも遥に穏やかな溶媒系で、脳神経系は完全に破壊されてしまいますから