伝染性単核球症コミュの伝染性単核球症からの慢性疲労症候群(ME/CFS)・線維筋痛症(FMS)の発症について

伝染性単核球症からの慢性疲労症候群の発症を示唆する記事を昨年見つけました。久しぶりに見ようとしたら、もうホームページが消えているようです。参考になるかと思いますので、保存してあった記事をコピーして紹介しようと思います。以下の通りです。

http://dodowild.sakura.ne.jp/koh/2009/07/10mecfs.html

:: DISMISSED :: 慢性疲労症候群(ME/CFS)・線維筋痛症(FMS)の情報
慢性疲労症候群(ME/CFS)・線維筋痛症(FMS)の研究・薬剤・患者等の情報
伝染性単核球症が、十代の若者の慢性疲労症候群(ME/CFS)に関与

Admin (2009年7月26日 12:11) | コメント(0) | トラックバック(0)
Reutersに、「"Mono" linked to chronic fatigue syndrome in teens」が掲載されました。

「伝染性単核球症に罹った301人の若者を調査したところ、その後13%が慢性疲労症候群(ME/CFS)を発症したと、米ノースウェスタン大学医学部が報告した等が記されています。」

※関連記事
About.com:Fibromyalgia & Chronic Fatigue Syndrome "Juvenile Chronic Fatigue Syndrome & the Mono Virus"
カテゴリ:

慢性疲労症候群(ME/CFS)研究情報

元々は、英語の２つのサイトにリンクが張られてました。長くなりますが消えるかもしれないので、引用したいと思います。

http://www.reuters.com/article/healthNews/idUSTRE56E8BE20090715?feedType=RSS&feedName=healthNews

"Mono" linked to chronic fatigue syndrome in teens
Michelle Rizzo
Wed Jul 15, 2009 7:32pm EDTNEW YORK (Reuters Health) - Teens who develop "mono," otherwise known as infectious mononucleosis, may be at risk for chronic fatigue syndrome, according to a study in Pediatrics.

Health

Previous studies suggested that about one in ten adults with acute infectious mononucleosis go on to develop chronic fatigue syndrome, Dr. Ben Z. Katz, of Northwestern University Feinberg School of Medicine, Chicago, and colleagues write. However, what happens to teens with mononucleosis is less well-studied.

The researchers monitored 301 adolescents with the infection. Six months after the mononucleosis diagnosis, 70 patients (24 percent) had not made a full recovery.

Thirty-nine of these subjects were diagnosed with chronic fatigue syndrome, reflecting 13 percent of the original group of 301.

Six months later, at a 12-month follow-up visit, 7 percent had chronic fatigue syndrome, and at 24 months, chronic fatigue syndrome persisted in 4 percent. That is about 20 times higher than in the general teenage population.

All 13 patients who still had chronic fatigue syndrome at 24 months were female and, on average, they reported worse fatigue at 12 months.

Treatment with steroids for the infectious mononucleosis at the time of its diagnosis did not affect the risk of developing chronic fatigue syndrome.

"As part of our study, we also followed a group of adolescents who completely recovered from their mononucleosis," Dr. Katz told Reuters Health.

"We are now in the process of trying to figure out what differentiates adolescents who recover from those who don't," he said.

SOURCE: Pediatrics, July 2009.

http://chronicfatigue.about.com/b/2009/07/07/mono-juvenile-chronic-fatigue-syndrome.htm

Fibromyalgia & CFS Blog
By Adrienne Dellwo, About.com Guide to Fibromyalgia & CFS

My BioMy BlogMy ForumAdd to: iGoogleMy Yahoo!RSS.See More About:chronic fatigue syndrome causeschronic fatigue syndrome researchchronic fatigue syndrome risk factors
Juvenile Chronic Fatigue Syndrome & the Mono Virus
Tuesday July 7, 2009

One of several viruses believed responsible for at least some cases of chronic fatigue syndrome (CFS or ME/CFS) is the Epstein-Barr virus, which can cause infectious mononucleosis (mono, or the "kissing disease") during adolescence or early adulthood. A new study shores up evidence that it's somehow involved, especially in juvenile cases.

Researchers looked at 301 kids between 12 and 18 who hadn't recovered from mono after 6 months. They examined them, then checked back with them at 12 and 24 months post-infection.

Some of the kids fit ME/CFS diagnostic criteria, but in shrinking numbers up to the 24-month mark. At that point, 13 of them still fit criteria. All of them were girls, and they'd reported more fatigue at the 12-month check-in.

Now that this link is established, researchers say more research needs to look at other post-mono risk factors.

I had mono quite severely in high school, and when I heard about chronic fatigue syndrome a couple of years later, my first thought was, "I've got that." I'm actually not diagnosed with ME/CFS, but I do fit the criteria and I've often wondered if I have a mild case. Studies like this make me think it's likely. I know my immune system changed after that 10-month illness, which ended when I had my tonsils out -- the doctor told me that without tonsils I'd be more immune to throat-related illnesses, like strep. I'd actually never had strep at that point, but afterward got it regularly for years. I've had constant throat problems for the past decade or so, as well.

Do you believe your ME/CFS was triggered by mono, or the Epstein-Barr virus? Have any anti-viral/immune system treatments helped you? Share your story so we can all learn from it -- leave a comment below!

こちらのサイトにコメントとして、体験談がたくさんのってます。さすがにコメントまで引用すると長くなりすぎるので割愛します。急性期としての伝染性単核球症は、一か月くらいで治るのでしょうが、こじらせるケースも多いようですね。ロイターの記事によると六か月後に２４％が完治せず、１３％が慢性疲労症候群と診断されたと書いてあるように思えます。私はあまり英語が得意ではないので、間違っていたら遠慮なくご教授いただければと思います。想像以上に比率が高いと感じました。

あと、危ない!「慢性疲労」 (生活人新書) 倉恒 弘彦 (著), 渡辺 恭良 (著), 井上 正康 (著) という本の１６７〜１７１ページに伝染性単核球症からの慢性疲労症候群の発症例が載ってました。参考になればと思います。